For a full list of publications from the Collins Laboratory, click here.

Recent Publications

Painter, M.M., Zimmerman, G.E. Merlino, M.S., Robertson, A.W., Terry, V.H., Ren, X., McLeod, M.R. Gomez-Rodriguez, L., Garcia, K.A., Leonard, J.A., Leopold, K.E., Neeval, A.J., Lubow, J.A., Olson, E., Piechocka-Trocha, A., Collins, D.R., Tripathi, A., Raghavan, M., Walker, B.D., Hurley, J.H., Sherman, D.H., and Collins K.L. Natural product counteracts HIV-1 Nef to enhance immune clearance of infected primary cells by cytotoxic T lymphocytes, (2020) Submitted.

Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages. Lubow J, Virgilio MC, Merlino M, Collins DR, Mashiba M, Peterson BG, Lukic Z, Painter MM, Gomez-Rivera F, Terry V, Zimmerman G, Collins KL. Elife. 2020 Mar 2;9. pii: e51035. doi: 10.7554/eLife.51035.PMID: 32119644

Zaikos TD, Terry VH, Sebastian Kettinger NT, Lubow J, Painter MM, Virgilio MC, Neevel A, Taschuk F, Onafuwa-Nuga A, McNamara LA, Riddell J 4th, Bixby D, Markowitz N, Collins KL. Hematopoietic Stem and Progenitor Cells Are a Distinct HIV Reservoir that Contributes to Persistent Viremia in Suppressed Patients. Cell Rep. 2018 Dec 26;25(13):3759-3773.e9. doi: 10.1016/j.celrep.2018.11.104. PubMed PMID: 30590047.

Zaikos TD, Painter MM, Sebastian Kettinger NT, Terry VH, Collins KL. Class 1-Selective Histone Deacetylase (HDAC) Inhibitors Enhance HIV Latency Reversal while Preserving the Activity of HDAC Isoforms Necessary for Maximal HIV Gene Expression. J Virol. 2018 Mar 15;92(6). doi: 10.1128/JVI.02110-17. Print 2018 Mar 15. PubMed PMID: 29298886; PubMed Central PMCID: PMC5827401.

Painter MM, Zaikos TD, Collins KL. Quiescence Promotes Latent HIV Infection and Resistance to Reactivation from Latency with Histone Deacetylase Inhibitors. J Virol. 2017 Dec 15;91(24). doi: 10.1128/JVI.01080-17. Print 2017 Dec 15. PubMed PMID: 29021396; PubMed Central PMCID: PMC5709582.

Sebastian NT, Zaikos TD, Terry V, Taschuk F, McNamara LA, Onafuwa-Nuga A, Yucha R, Signer RAJ, Riddell J IV, Bixby D, Markowitz N, Morrison SJ, Collins KL. CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo. PLoS Pathog. 2017 Jul;13(7):e1006509. doi: 10.1371/journal.ppat.1006509. eCollection 2017 Jul. PubMed PMID: 28732051; PubMed Central PMCID: PMC5540617.


Collins DR, Lubow J, Lukic Z, Mashiba M, Collins KL. Vpr Promotes Macrophage-Dependent HIV-1 Infection of CD4+ T Lymphocytes. PLoS Pathog. 2015 Jul;11(7):e1005054. doi: 10.1371/journal.ppat.1005054. eCollection 2015 Jul. PubMed PMID: 26186441; PubMed Central PMCID: PMC4506080.

Carter CC, Onafuwa-Nuga A, McNamara LA, Riddell J 4th, Bixby D, Savona MR, Collins KL. HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs. Nat Med. 2010 Apr;16(4):446-51. doi: 10.1038/nm.2109. Epub 2010 Mar 7. PubMed PMID: 20208541; PubMed Central PMCID: PMC2892382.

Collins KL, Chen BK, Kalams SA, Walker BD, Baltimore D. HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. Nature. 1998 Jan 22;391(6665):397-401. doi: 10.1038/34929. PubMed PMID: 9450757.

Review Articles

Virgilio MC, Collins KL. The Impact of Cellular Proliferation on the HIV-1 Reservoir. Viruses. 2020 Jan 21;12(2). pii: E127. doi: 10.3390/v12020127. Review.PubMed PMID: 31973022.

Sebastian NT, Collins KL. Targeting HIV latency: resting memory T cells, hematopoietic progenitor cells and future directions.Expert Rev Anti Infect Ther. 2014 Oct;12(10):1187-201. doi: 10.1586/14787210.2014.956094. Epub 2014 Sep 4. Review. PubMed PMID: 25189526; PubMed Central PMCID: PMC4291319.

Zaikos TD, Collins KL. Long-lived reservoirs of HIV-1. Trends Microbiol. 2014 Apr;22(4):173-5. doi: 10.1016/j.tim.2014.02.015. Epub 2014 Mar 15. PubMed PMID: 24641995; PubMed Central PMCID: PMC4048589.

Collins DR, Collins KL. HIV-1 accessory proteins adapt cellular adaptors to facilitate immune evasion. PLoS Pathog. 2014 Jan;10(1):e1003851. doi: 10.1371/journal.ppat.1003851. Epub 2014 Jan 23. Review. PubMed PMID: 24465204; PubMed Central PMCID: PMC3900642.